just test it out.
some setups will work fine with wayland and some will work better with xorg.
there are of course ways solve those issues, but it’s easier to test both and use the one that works best for you.
wayland is the future, but the present is whatever works best for you.
this is not audio specific but just an FYI, reinstalling does nothing on an updated system unless the program files were corrupted somehow, which is not normal.
to really reinstall a program from scratch you have to use apt-get purge or apt purge to ensure that global configurations files are removed, and pay attention to the logs printed out because some files may not be removed.
then, you have to manually delete your user configuration files for those programs, or create a new user un your computer to test it out first to see if user config files are generating any troubles.