Well, the title is a question and the answer is: Not quite but near enough.
A title has to catch interest, and in this case I would not say that it is click bait because in the end he kind of put a “Linux” on the “NES”.
I tend to be forgiving when the content behind the click bait title is good, like it is here.
It looks like an issue with the premade Lutris installer/config package.
Can you try downloading the installer from GOG and install manually in Lutris via the “Install a Windows Game from an executable” (the + button on the top left) option?
There you can choose “Windows XP 32bit” as an Installer preset, this should provide the best compatibility.