Prion diseases would be harder because things circulating in your blood don’t always enter your brain (thanks to your astrocytes, which help protect your neurons). But if you can get the right cells to produce the right protein, you can do a lot of amazing things.
https://en.wikipedia.org/wiki/Immunotherapy?wprov=sfla1
Immunotherapy is crazy.
Prion diseases would be harder because things circulating in your blood don’t always enter your brain (thanks to your astrocytes, which help protect your neurons). But if you can get the right cells to produce the right protein, you can do a lot of amazing things.